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Human CellExp™ NOV, human recombinant

Nephroblastoma Overexpressed gene, CCN3, IGFBP9, NovH

     
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Product info
Primary Accession P48745
Calculated MW 20-50 kDa
Additional Info
Gene ID 4856
Other Names Nephroblastoma Overexpressed gene, CCN3, IGFBP9, NovH
Gene Source Human
Source CHO cells
Assay&Purity SDS-PAGE;> 95%
Assay2&Purity2 HPLC;> 95%
Recombinant Yes
Sequence TQRCPPQCPG RCPATPPTCA PGVRAVLDGC SCCLVCARQR GESCSDLEPC DESSGLYCDR SADPSNQTGI CTAVEGDNCV FDGVIYRSGE KFQPSCKFQC TCRDGQIGCV PRCQLDVLLP EPNCPAPRKV EVPGECCEKW ICGPDEEDSL GGLTLAAYRP EATLGVEVSD SSVNCIEQTT EWTACSKSCG MGFSTRVTNR NRQCEMLKQT RLCMVRPCEQ EPEQPTDKKG KKCLRTKKSL KAIHLQFKNC TSLHTYKPRF CGVCSDGRCC TPHNTKTIQA EFQCSPGQIV KKPVMVIGTC TCHTNCPKNN EAFLQELELK TTRGKM
Target/Specificity NOV
Application Notes Reconstituted in ddH2O at 100 µg/mL.
Format Lyophilized
Storage -20°C;Lyophilized after extensive dialysis against PBS.
Citations (0)

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Background

Nephroblastoma Overexpressed Gene Protein (NOV), also known as CCN3, IGFBP9 and NOVH, is one of the CCN family of secreted proteins. It is expressed in bone marrow, thymic cells and nephroblastoma. NOV signals through integrin receptors, NOTCH1 and fibulin 1c to regulate multiple cellular activities, such as cell adhesion, migration, proliferation and differentiation. The reported functions of NOV are diverse. It has been reported to play a role in angiogenesis and stem cell self-renewal. It has also been implicated in osteogenic differentiation, embryo development and cancer pathogenesis.

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$ 135.00
$ 225.00
Cat# PBV11499r-10
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