BAIAP2, Human recombinant
Brain-specific angiogenesis inhibitor 1-associated protein 2, BAI1-associated protein 2, Protein BAP
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9UQB8 |
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Calculated MW | 58.4 kDa |
Gene ID | 10458 |
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Other Names | Brain-specific angiogenesis inhibitor 1-associated protein 2, BAI1-associated protein 2, Protein BAP2, Fas ligand-associated factor 3, Insulin receptor substrate p53/p58, Insulin receptor substrate protein of 53kDa, FLAF3, IRS-58, IRSp53/58, IRSP53. |
Gene Source | Human |
Source | E. coli |
Assay&Purity | SDS-PAGE;> 95% |
Recombinant | Yes |
Target/Specificity | BAIAP2 |
Application Notes | Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. |
Format | Liquid |
Storage | -80°C;In 20mM Tris-HCl buffer (pH 8.0), 0.1 M NaCl, 1mM DTT and 30% glycerol. |
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Provided below are standard protocols that you may find useful for product applications.
Background
BAIAP2 is a ubiquitous regulator of the actin cytoskeleton. Controlled by the Rho-family GTPases BAIAP2 facilitates filopodia development. BAIAP2 is expressed in the cytoplasm and binds small membrane-bound G-proteins to cytoplasmic effector proteins and operates as an insulin receptor tyrosine kinase substrate. BAIAP2 proposes a part for insulin in the central nervous system and was identified as interacting with the dentatorubral pallidoluysian atrophy gene, which is related to an autosomal dominant neurodegenerative disease.
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