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Galectin-3, mouse recombinant

Lectin, galactose binding, soluble 3, CBP35, GAL3, GALBP, GALIG, LGALS2, MAC2

     
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Product info
Primary Accession Q8C253
Calculated MW 29.8 kDa
Additional Info
Other Names CBP35, GAL3, GALBP, GALIG, LGALS2, MAC2.
Gene Source Mouse
Source E. coli
Assay&Purity SDS-PAGE;> 95%
Recombinant Yes
Sequence MGSSHHHHHH SSGLVPRGSH MGSMADSFSL NDALAGSGNP NPQGYPGAWG NQPGAGGYPG AAYPGAYPGQ APPGAYPGQA PPGAYPGQAP PSAYPGPTAPGAYPGPTAPG AYPGSTAPGA FPGQPGAPGA YPSAPGGYPA AGPYGVPAGP LTVPYDLPLP GGVMPRMLIT IMGTVKPNAN RIVLDFRRGN DVAFHFNPRFNENNRRVIVC NTKQDNNWGK EERQSAFPFE SGKPFKIQVL VEADHFKVAV NDAHLLQYNH RMKNLREISQ LGISGDITLT SANHAMI
Target/Specificity Lgals3
Format Liquid
Storage -20°C;In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 50% glycerol,1mM DTT, 2mM EDTA
Citations (0)

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Background

LGALS3, also known as galectin 3, is a member of the family of animal lectins, which selectively binds betagalactosidemresidues. This protein is secreted from cells by ectocytosis, which is independent of the classical secretory pathway through the endoplasmic reticulum/Golgi network. LGALS3 has been associated with the inhibition of apoptosis and the progression of cancer. It is normally distributed in epithelia of many organs, in various inflammatory cells, including macrophages, as well as dendritic cells and Kupffer cells. The expression of this lectin is up-regulated during inflammation, cell proliferation, cell differentiation and through trans-activation by viral proteins. Recombinant mouse LGALS3 protein, used to Histag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

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$ 105.00
$ 495.00
Cat# PBV11525r-10
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