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Galectin-2, mouse recombinant
Lgals2, 2200008F12Rik, AI324147, Gal-2
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9CQW5 |
|---|---|
| Calculated MW | 17.3 kDa |
| Other Names | Lgals2, 2200008F12Rik, AI324147 |
|---|---|
| Gene Source | Mouse |
| Source | E. coli |
| Assay&Purity | SDS-PAGE;> 95% |
| Recombinant | Yes |
| Sequence | MGSSHHHHHH SSGLVPRGSH MGSMSEKFEV KDLNMKPGMS LKIKGKIHND VDRFLINLGQ GKETLNLHFN PRFDESTIVC NTSEGGRWGQ EQRENHMCFS PGSEVKITIT FQDKDFKVTL PDGHQLTFPN RLGHNQLHYL SMGGLQISSF KLE |
| Target/Specificity | Lgals2 |
| Format | Liquid |
| Storage | -20°C;In 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol, 1mM DTT |
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Provided below are standard protocols that you may find useful for product applications.
Background
Galectin 2, also known as Lgals2, belongs to the galectins family. Galectins are a family of soluble beta-galactoside-binding animal lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. Lgals2 is a monomeric or homodimeric prototype galectin that is expressed in hepatoma, stomach epithelial cells and in colorectal and neural tumors. It induces apoptosis in activated T cells and binds to the cytokine lymphotoxin-a (LTA) with possible implications in risk of myocardial infarction. Human and mouse Lgals2 share approximately 65% amino acid sequence similarity. Recombinant Mouse Lgals2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
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