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Human CellExp™ Glypican 3 / GPC3, Human recombinant
Glypican-3, GTR2-2, Intestinal protein OCI-5, MXR7, GPC3, OCI5
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P51654 |
|---|---|
| Calculated MW | 61.7 kDa |
| Gene ID | 2719 |
|---|---|
| Other Names | GPC3, OCI5, Glypican-3, GTR2-2, MXR7, DGSX, SDYS, SGB, SGBS, SGBS1 |
| Gene Source | Human |
| Source | HEK 293 cells |
| Assay&Purity | SDS-PAGE;> 90% |
| Recombinant | Yes |
| Target/Specificity | GPC3 |
| Application Notes | Reconstitute in 1X PBS to the desired protein concentration. |
| Format | Lyophilized |
| Storage | -20°C;Lyophilized from 0.22 µm filtered solution in PBS, pH7.4. Normally Trehalose is added as protectant before lyophilization. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.
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