Human CellExp™ GITR Ligand / TNFSF18 Fc Tag, Mouse recombinant
TNFSF18, AITRL, TL6, hGITRL, GITR Ligand
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q7TS55 |
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Calculated MW | 41.4 kDa |
Gene ID | 240873 |
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Other Names | TNFSF18, AITRL, TL6, hGITRL, GITR Ligand |
Gene Source | Mouse |
Source | HEK 293 cells |
Assay&Purity | SDS-PAGE;> 95% |
Recombinant | Yes |
Target/Specificity | Tnfsf18 |
Application Notes | Reconstitute in sterile deionized water to the desired protein concentration. |
Format | Lyophilized |
Storage | -20°C;Lyophilized from 0.22 µm filtered solution in PBS, pH7.4. Normally Trehalose is added as protectant before lyophilization. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Tumor necrosis factor ligand superfamily member 18 (TNFSF18) is also known as Glucocorticoid - induced TNF-related ligand (GITRL or GITR Ligand), Activation - inducible TNF - related ligand (AITRL), which belongs to the tumor necrosis factor family. TNFSF18 is expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. TNFSF18 / GITRL is up-regulated after stimulation by bacterial lipopolysaccharides (LPS). TNFSF18 Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. TNFSF18 / GITR Ligand is important for interactions between activated T-lymphocytes and endothelial cells. TNFSF18 also mediates activation of NF-kappa-B.
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