Human Inosine-5′-Monophosphate Dehydrogenase II, human recombinant
IMP dehydrogenase type II, IMPDH II, IMPD2, IMPDH
|Calculated MW||57 kDa|
|Other Names||IMP dehydrogenase type II, IMPDH II, IMPD2, IMPDH|
|Storage||-20°C;20 mM Tris, pH 8.0, 150 mM NaCl, 2mM DTT, 2mM EDTA and 20% glycerol|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Inosine monophosphate dehydrogenase, IMPDH, (E.C. 22.214.171.124) is the rate-limiting enzyme in de novo guanine nucleotide biosynthesis and it is essential for lymphocyte proliferation. IMPDH oxidizes inosine 5’-monophosphate (IMP) to xanthine 5’-monophosphate (XMP) using NAD as a cofactor. It plays a critical role in cell growth and in the malignancy of some tumors. IMPDH II is the predominant isoform of IMPDH and is specifically linked to a wide range of cancers and lymphocyte proliferation. BioVision’s active human IMPDH II is suitable for functional assays, high-throughput screening and preclinical studies in drug discovery.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.