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Human CellExp™ TYRO3 / Dtk, Human recombinant

UCHL3, Ubiquitin thioesterase L3

     
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Product info
Primary Accession Q06418
Calculated MW 68.2 kDa
Additional Info
Gene ID 7301
Other Names UCHL3, Ubiquitin thioesterase L3
Gene Source Human
Source HEK 293 cells
Assay&Purity SDS-PAGE;> 95%
Recombinant Yes
Target/Specificity TYRO3
Application Notes Reconstitute in sterile deionized water to the desired protein concentration.
Format Lyophilized
Storage -20°C;Lyophilized from 0.22 µm filtered solution in PBS, pH7.4. Normally Trehalose is added as protectant before lyophilization.
Citations (0)

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Background

Tyrosine-protein kinase receptor TYRO3 is also known as Tyrosine-protein kinase BYK, DTK, RSE, SKY, TIF, which belongs to the protein kinase superfamily, Tyr protein kinase family and AXL/UFO subfamily. TYRO3 regulates many physiological processes including cell survival, migration and differentiation. TYRO3 activates the AKT survival pathway, including nuclear translocation of NF-kappa-B and up-regulation of transcription of NF-kappa-B-regulated genes. TYRO3 interacts (via N-terminus) with extracellular ligands TULP1 and GAS6 By similarity and also interacts with PIK3R1, this interaction increases PI3-kinase activity.

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$ 95.00
$ 375.00
Cat# PBV11616r-20
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