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AASS predesign siRNASynthetic RNA

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Ordering Information
Catalog # Size Availability Price  
RI10007 5 OD 400 ul 13-15 days $ 110.00 Add to cart
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AASS predesign siRNA - Additional info

Gene ID10157
Gene SymbolAASS
Other Names
LKRSDH, LORSDH, LKR/SDH, AASS
Format
HPLC purified siRNA is supplied as a dried pellet in nmol quantities.
Storage
Maintain refrigerated at 2-8°C for up to one week. For long term storage store at -20°C.
Precautions
This product is for research use only. Not for use in diagnostic or therapeutic procedures.

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Provided below are standard protocols that you may find useful for product applications.

BACKGROUND

This gene encodes a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in this gene are associated with familial hyperlysinemia.

REFERENCES

Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039. The DNA sequence of human chromosome 7. Hillier LW, et al. Nature, 2003 Jul 10. PMID 12853948. Human chromosome 7: DNA sequence and biology. Scherer SW, et al. Science, 2003 May 2. PMID 12690205. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.