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AATF predesign siRNASynthetic RNA
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| RI10008 | 5 OD 400 ul | 13-15 days | $ 110.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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AATF predesign siRNA - Additional info | |
| Gene ID | 26574 |
| Gene Symbol | AATF |
| Other Names DED, CHE1, CHE-1, AATF | |
| Format HPLC purified siRNA is supplied as a dried pellet in nmol quantities. | |
| Storage Maintain refrigerated at 2-8°C for up to one week. For long term storage store at -20°C. | |
| Precautions This product is for research use only. Not for use in diagnostic or therapeutic procedures. | |
AATF predesign siRNA - Related products
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BACKGROUND
The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis.
REFERENCES
Mutation analysis of the AATF gene in breast cancer families. Haanpää M, et al. BMC Cancer, 2009 Dec 21. PMID 20025740. Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging. Wheeler HE, et al. PLoS Genet, 2009 Oct. PMID 19834535. Cellular AATF gene: armour against HIV-1. Kaul D. Indian J Biochem Biophys, 2007 Oct. PMID 18341201. Che-1 activates XIAP expression in response to DNA damage. Bruno T, et al. Cell Death Differ, 2008 Mar. PMID 18049476. Toward a confocal subcellular atlas of the human proteome. Barbe L, et al. Mol Cell Proteomics, 2008 Mar. PMID 18029348.
