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ABCC1 predesign siRNASynthetic RNA
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| RI10020 | 5 OD 400 ul | 13-15 days | $ 110.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
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- Backgrounds
ABCC1 predesign siRNA - Additional info | |
| Gene ID | 4363 |
| Gene Symbol | ABCC1 |
| Other Names MRP, ABCC, GS-X, MRP1, ABC29, DKFZp781G125, DKFZp686N04233, ABCC1 | |
| Format HPLC purified siRNA is supplied as a dried pellet in nmol quantities. | |
| Storage Maintain refrigerated at 2-8°C for up to one week. For long term storage store at -20°C. | |
| Precautions This product is for research use only. Not for use in diagnostic or therapeutic procedures. | |
ABCC1 predesign siRNA - Related products
AP6596b: ABCC1 Antibody (C-term)
RI10020: ABCC1 predesign siRNA
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BACKGROUND
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternative splicing by exon deletion results in several splice variants but maintains the original open reading frame in all forms.
REFERENCES
Polymorphisms in the multiple drug resistance protein 1 and in P-glycoprotein 1 are associated with time to event outcomes in patients with advanced multiple myeloma treated with bortezomib and pegylated liposomal doxorubicin. Buda G, et al. Ann Hematol, 2010 Jun 8. PMID 20532504. MRP1 polymorphisms associated with citalopram response in patients with major depression. Lee SH, et al. J Clin Psychopharmacol, 2010 Apr. PMID 20520284. Multidrug resistance-associated protein-1 (MRP1) genetic variants, MRP1 protein levels and severity of COPD. Budulac SE, et al. Respir Res, 2010 May 20. PMID 20487524. A Large-scale genetic association study of esophageal adenocarcinoma risk. Liu CY, et al. Carcinogenesis, 2010 Jul. PMID 20453000. Influence of Etoposide on anti-apoptotic and multidrug resistance-associated protein genes in CD133 positive U251 glioblastoma stem-like cells. Jin F, et al. Brain Res, 2010 Jun 8. PMID 20388502.
