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ABCF1 predesign siRNASynthetic RNA

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United States
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Ordering Information
Catalog # Size Availability Price  
RI10027 5 OD 400 ul 13-15 days $ 110.00 Add to cart
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ABCF1 predesign siRNA - Additional info

Gene ID23
Gene SymbolABCF1
Other Names
ABC27, ABC50, ABCF1
Format
HPLC purified siRNA is supplied as a dried pellet in nmol quantities.
Storage
Maintain refrigerated at 2-8°C for up to one week. For long term storage store at -20°C.
Precautions
This product is for research use only. Not for use in diagnostic or therapeutic procedures.

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Provided below are standard protocols that you may find useful for product applications.

BACKGROUND

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the GCN20 subfamily. Unlike other members of the superfamily, this protein lacks the transmembrane domains which are characteristic of most ABC transporters. This protein may be regulated by tumor necrosis factor-alpha and play a role in enhancement of protein synthesis and the inflammation process.

REFERENCES

HLA-E gene polymorphism associates with ankylosing spondylitis in Sardinia. Paladini F, et al. Arthritis Res Ther, 2009. PMID 19912639. High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. Barcellos LF, et al. PLoS Genet, 2009 Oct. PMID 19851445. ABC50 promotes translation initiation in mammalian cells. Paytubi S, et al. J Biol Chem, 2009 Sep 4. PMID 19570978. Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects. Saito A, et al. J Hum Genet, 2009 Jun. PMID 19343046. The N-terminal region of ABC50 interacts with eukaryotic initiation factor eIF2 and is a target for regulatory phosphorylation by CK2. Paytubi S, et al. Biochem J, 2008 Jan 1. PMID 17894550.