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ACADM predesign siRNASynthetic RNA
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| RI10041 | 5 OD 400 ul | 13-15 days | $ 110.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
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ACADM predesign siRNA - Additional info | |
| Gene ID | 34 |
| Gene Symbol | ACADM |
| Other Names MCAD, ACAD1, MCADH, FLJ18227, FLJ93013, FLJ99884, ACADM | |
| Format HPLC purified siRNA is supplied as a dried pellet in nmol quantities. | |
| Storage Maintain refrigerated at 2-8°C for up to one week. For long term storage store at -20°C. | |
| Precautions This product is for research use only. Not for use in diagnostic or therapeutic procedures. | |
ACADM predesign siRNA - Related products
AP6827b: ACADM Antibody (C-term)
AP6827c: ACADM Antibody (Center)
RI10041: ACADM predesign siRNA
DC01760: Human ACADM cDNA Clone
LY11479a: ACADM Over-expression Lysate
BP6827b: ACADM Antibody (C-term) Blocking Peptide
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Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
REFERENCES
A genome-wide perspective of genetic variation in human metabolism. Illig T, et al. Nat Genet, 2010 Feb. PMID 20037589. A novel tandem mass spectrometry method for rapid confirmation of medium- and very long-chain acyl-CoA dehydrogenase deficiency in newborns. ter Veld F, et al. PLoS One, 2009 Jul 30. PMID 19649258. Defining the human deubiquitinating enzyme interaction landscape. Sowa ME, et al. Cell, 2009 Jul 23. PMID 19615732. A985G mutation incidence in the medium-chain acyl-CoA dehydrogenase (MCAD) gene in Brazil. Ferreira AC, et al. Genet Mol Res, 2009 May 5. PMID 19551636. Protein misfolding is the molecular mechanism underlying MCADD identified in newborn screening. Maier EM, et al. Hum Mol Genet, 2009 May 1. PMID 19224950.
