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ACADS predesign siRNASynthetic RNA
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| RI10042 | 5 OD 400 ul | 13-15 days | $ 110.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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ACADS predesign siRNA - Additional info | |
| Gene ID | 35 |
| Gene Symbol | ACADS |
| Other Names SCAD, ACAD3, ACADS | |
| Format HPLC purified siRNA is supplied as a dried pellet in nmol quantities. | |
| Storage Maintain refrigerated at 2-8°C for up to one week. For long term storage store at -20°C. | |
| Precautions This product is for research use only. Not for use in diagnostic or therapeutic procedures. | |
ACADS predesign siRNA - Related products
AP8712b: ACADS Antibody (C-term)
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BACKGROUND
This gene encodes a a tetrameric mitochondrial flavoprotein, which is a member of the acyl-CoA dehydrogenase family. This enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Mutations in this gene have been associated with Short Chain Acyl-CoA Dehydrogenase Deficiency.
REFERENCES
Molecular pathogenesis of a novel mutation, G108D, in short-chain acyl-CoA dehydrogenase identified in subjects with short-chain acyl-CoA dehydrogenase deficiency. Shirao K, et al. Hum Genet, 2010 Jun. PMID 20376488. Misfolding of short-chain acyl-CoA dehydrogenase leads to mitochondrial fission and oxidative stress. Schmidt SP, et al. Mol Genet Metab, 2010 Jun. PMID 20371198. CLOCK is suggested to associate with comorbid alcohol use and depressive disorders. Sj?holm LK, et al. J Circadian Rhythms, 2010 Jan 21. PMID 20180986. A genome-wide perspective of genetic variation in human metabolism. Illig T, et al. Nat Genet, 2010 Feb. PMID 20037589. NPAS2 and PER2 are linked to risk factors of the metabolic syndrome. Englund A, et al. J Circadian Rhythms, 2009 May 26. PMID 19470168.
