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ACADVL predesign siRNASynthetic RNA
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| RI10044 | 5 OD 400 ul | 13-15 days | $ 110.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
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- Backgrounds
ACADVL predesign siRNA - Additional info | |
| Gene ID | 37 |
| Gene Symbol | ACADVL |
| Other Names ACAD6, LCACD, VLCAD, ACADVL | |
| Format HPLC purified siRNA is supplied as a dried pellet in nmol quantities. | |
| Storage Maintain refrigerated at 2-8°C for up to one week. For long term storage store at -20°C. | |
| Precautions This product is for research use only. Not for use in diagnostic or therapeutic procedures. | |
ACADVL predesign siRNA - Related products
AP6597a: ACADVL Antibody (N-term)
RI10044: ACADVL predesign siRNA
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Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
The protein encoded by this gene is targeted to the inner mitochondrial membrane where it catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. This acyl-Coenzyme A dehydrogenase is specific to long-chain and very-long-chain fatty acids. A deficiency in this gene product reduces myocardial fatty acid beta-oxidation and is associated with cardiomyopathy. Alternative splicing results in multiple transcript variants encoding different isoforms.
REFERENCES
Differential gene expression identified in Uigur women cervical squamous cell carcinoma by suppression subtractive hybridization. Pan Z, et al. Neoplasma, 2010. PMID 20099975. Compared effects of missense mutations in Very-Long-Chain Acyl-CoA Dehydrogenase deficiency: Combined analysis by structural, functional and pharmacological approaches. Gobin-Limballe S, et al. Biochim Biophys Acta, 2010 May. PMID 20060901. Dysregulation of very long chain acyl-CoA dehydrogenase coupled with lipid peroxidation. Kabuyama Y, et al. Am J Physiol Cell Physiol, 2010 Jan. PMID 19889959. Diagnostic assessment and long-term follow-up of 13 patients with Very Long-Chain Acyl-Coenzyme A dehydrogenase (VLCAD) deficiency. Lafor?t P, et al. Neuromuscul Disord, 2009 May. PMID 19327992. Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations. Lu Y, et al. J Lipid Res, 2008 Dec. PMID 18660489.
