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AMBP predesign siRNASynthetic RNA

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United States
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Ordering Information
Catalog # Size Availability Price  
RI10267 5 OD 400 ul 13-15 days $ 110.00 Add to cart
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AMBP predesign siRNA - Additional info

Gene ID259
Gene SymbolAMBP
Other Names
A1M, HCP, ITI, UTI, EDC1, HI30, ITIL, IATIL, ITILC, AMBP
Format
HPLC purified siRNA is supplied as a dried pellet in nmol quantities.
Storage
Maintain refrigerated at 2-8°C for up to one week. For long term storage store at -20°C.
Precautions
This product is for research use only. Not for use in diagnostic or therapeutic procedures.

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Provided below are standard protocols that you may find useful for product applications.

BACKGROUND

This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes.

REFERENCES

Bikunin and alpha(1)-microglobulin/bikunin precursor (AMBP) gene mutational screening in patients with kidney stones: a case-control study. Igci M, et al. Scand J Urol Nephrol, 2010 Jul 5. PMID 20602574. Bikunin loss in urine as useful marker for bladder carcinoma. Tsui KH, et al. J Urol, 2010 Jan. PMID 19914646. Increased levels of cell-free hemoglobin, oxidation markers, and the antioxidative heme scavenger alpha(1)-microglobulin in preeclampsia. Olsson MG, et al. Free Radic Biol Med, 2010 Jan 15. PMID 19879940. Clinical and prognostic significance of urinary trypsin inhibitor in patients with hepatocellular carcinoma after hepatectomy. Kikuchi I, et al. Ann Surg Oncol, 2009 Oct. PMID 19636634. Down-regulation of matriptase by overexpression of bikunin attenuates cell invasion in prostate carcinoma cells. Tsui KH, et al. Anticancer Res, 2008 Jul-Aug. PMID 18649735.