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BOK predesign siRNASynthetic RNA
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| RI10626 | 5 OD 400 ul | 13-15 days | $ 110.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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BOK predesign siRNA - Additional info | |
| Gene ID | 666 |
| Gene Symbol | BOK |
| Other Names BOKL, BCL2L9, MGC4631, BOK | |
| Format HPLC purified siRNA is supplied as a dried pellet in nmol quantities. | |
| Storage Maintain refrigerated at 2-8°C for up to one week. For long term storage store at -20°C. | |
| Precautions This product is for research use only. Not for use in diagnostic or therapeutic procedures. | |
BOK predesign siRNA - Related products
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BACKGROUND
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains all four BCL-2 like domains (BH1, 2, 3 and 4) and is a pro-apoptotic BCL-2 protein identified in the ovary.
REFERENCES
Voxelwise genome-wide association study (vGWAS). Stein JL, et al. Neuroimage, 2010 Feb 17. PMID 20171287. Mtd/Bok takes a swing: proapoptotic Mtd/Bok regulates trophoblast cell proliferation during human placental development and in preeclampsia. Ray JE, et al. Cell Death Differ, 2010 May. PMID 19942931. A natural antisense transcript, BOKAS, regulates the pro-apoptotic activity of human Bok. Zhang H, et al. Int J Oncol, 2009 Apr. PMID 19287972. Bok, Bcl-2-related Ovarian Killer, Is Cell Cycle-regulated and Sensitizes to Stress-induced Apoptosis. Rodriguez JM, et al. J Biol Chem, 2006 Aug 11. PMID 16772296. Nuclear translocation of the pro-apoptotic Bcl-2 family member Bok induces apoptosis. Bartholomeusz G, et al. Mol Carcinog, 2006 Feb. PMID 16302269.
