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CGB predesign siRNASynthetic RNA
| Country | United States
Ordering Information
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|---|---|---|---|---|
| Catalog # | Size | Availability | Price | |
| RI11028 | 5 OD 400 ul | 13-15 days | $ 110.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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CGB predesign siRNA - Additional info | |
| Gene ID | 1082 |
| Gene Symbol | CGB |
| Other Names CGB3, CGB5, CGB7, CGB8, hCGB, CGB | |
| Format HPLC purified siRNA is supplied as a dried pellet in nmol quantities. | |
| Storage Maintain refrigerated at 2-8°C for up to one week. For long term storage store at -20°C. | |
| Precautions This product is for research use only. Not for use in diagnostic or therapeutic procedures. | |
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BACKGROUND
This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene.
REFERENCES
TCR mimic monoclonal antibody targets a specific peptide/HLA class I complex and significantly impedes tumor growth in vivo using breast cancer models. Verma B, et al. J Immunol, 2010 Feb 15. PMID 20065111. Expression and regulation by PPARgamma of hCG alpha- and beta-subunits: comparison between villous and invasive extravillous trophoblastic cells. Handschuh K, et al. Placenta, 2009 Dec. PMID 19846218. Beta-human chorionic gonadotropin production associated with phyllodes tumor of the breast: an unusual paraneoplastic phenomenon. Reisenbichler ES, et al. Breast J, 2009 Sep-Oct. PMID 19624411. Purification of three major forms of beta-hCG from urine and production of polyclonal antibodies against them. Khademi F, et al. Clin Biochem, 2009 Sep. PMID 19501580. Effect of maternal smoking on cord blood estriol, placental lactogen, chorionic gonadotropin, FSH, LH, and cortisol. Varvarigou AA, et al. J Perinat Med, 2009. PMID 19290844.