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DAPK2 predesign siRNASynthetic RNA
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| RI11410 | 5 OD 400 ul | 13-15 days | $ 110.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
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DAPK2 predesign siRNA - Additional info | |
| Gene ID | 23604 |
| Gene Symbol | DAPK2 |
| Other Names DRP1, DRP-1, MGC119312, DAPK2 | |
| Format HPLC purified siRNA is supplied as a dried pellet in nmol quantities. | |
| Storage Maintain refrigerated at 2-8°C for up to one week. For long term storage store at -20°C. | |
| Precautions This product is for research use only. Not for use in diagnostic or therapeutic procedures. | |
DAPK2 predesign siRNA - Related products
AP7033a: DAPK2 Antibody (N-term)
AP7218a: DAPK2 Antibody (N-term V55)
RI11410: DAPK2 predesign siRNA
DC09933: Human DAPK2 cDNA Clone
LY12169a: DAPK2 Over-expression Lysate
BP7033a: DAPK2 Antibody (N-term) Blocking Peptide
BP7218a: DAPK2 Antibody (N-term V55) Blocking Peptide
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BACKGROUND
This gene encodes a protein that belongs to the serine/threonine protein kinase family. This protein contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain with significant similarity to that of death-associated protein kinase 1 (DAPK1), a positive regulator of programmed cell death. Overexpression of this gene was shown to induce cell apoptosis. It uses multiple polyadenylation sites.
REFERENCES
Inactivation of RASSF1A, RARbeta2 and DAP-kinase by promoter methylation correlates with lymph node metastasis in nasopharyngeal carcinoma. Fendri A, et al. Cancer Biol Ther, 2009 Mar. PMID 19221469. Down-regulation of death-associated protein kinase-2 is required for beta-catenin-induced anoikis resistance of malignant epithelial cells. Li H, et al. J Biol Chem, 2009 Jan 23. PMID 18957423. DAPK2 is a novel E2F1/KLF6 target gene involved in their proapoptotic function. Britschgi A, et al. Oncogene, 2008 Sep 25. PMID 18521079. The death-associated protein kinase 2 is up-regulated during normal myeloid differentiation and enhances neutrophil maturation in myeloid leukemic cells. Rizzi M, et al. J Leukoc Biol, 2007 Jun. PMID 17347302. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. Olsen JV, et al. Cell, 2006 Nov 3. PMID 17081983.
