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DAPK3 predesign siRNASynthetic RNA

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United States
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Ordering Information
Catalog # Size Availability Price  
RI11411 5 OD 400 ul 13-15 days $ 110.00 Add to cart
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DAPK3 predesign siRNA - Additional info

Gene ID1613
Gene SymbolDAPK3
Other Names
ZIP, ZIPK, FLJ36473, DAPK3
Format
HPLC purified siRNA is supplied as a dried pellet in nmol quantities.
Storage
Maintain refrigerated at 2-8°C for up to one week. For long term storage store at -20°C.
Precautions
This product is for research use only. Not for use in diagnostic or therapeutic procedures.

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Provided below are standard protocols that you may find useful for product applications.

BACKGROUND

Death-associated protein kinase 3 (DAPK3) induces morphological changes in apoptosis when overexpressed in mammalian cells. These results suggest that DAPK3 may play a role in the induction of apoptosis.

REFERENCES

Link of Dlk/ZIP kinase to cell apoptosis and tumor suppression. Wu Y, et al. Biochem Biophys Res Commun, 2010 Feb 19. PMID 20085750. Downregulation of ZIP kinase is associated with tumor invasion, metastasis and poor prognosis in gastric cancer. Bi J, et al. Int J Cancer, 2009 Apr 1. PMID 19117059. Physical and functional interactions between ZIP kinase and UbcH5. Ohbayashi N, et al. Biochem Biophys Res Commun, 2008 Aug 8. PMID 18515077. ZIP kinase plays a crucial role in androgen receptor-mediated transcription. Leister P, et al. Oncogene, 2008 May 22. PMID 18084323. Novel ZIP kinase isoform lacks leucine zipper. Takamoto N, et al. Arch Biochem Biophys, 2006 Dec 15. PMID 17126281.