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EN2 predesign siRNASynthetic RNA
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| RI11770 | 5 OD 400 ul | 13-15 days | $ 110.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
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- Backgrounds
EN2 predesign siRNA - Additional info | |
| Gene ID | 2020 |
| Gene Symbol | EN2 |
| Other Names EN2 | |
| Format HPLC purified siRNA is supplied as a dried pellet in nmol quantities. | |
| Storage Maintain refrigerated at 2-8°C for up to one week. For long term storage store at -20°C. | |
| Precautions This product is for research use only. Not for use in diagnostic or therapeutic procedures. | |
EN2 predesign siRNA - Related products
AP7457a: EN2 Antibody (N-term)
AP7457b: EN2 Antibody (C-term)
AP7457d: EN2 Antibody (C-term-2)
AP7457e: EN2 Antibody (N-term)
AP7457f: EN2 Antibody (C-term)
BP7457a: EN2 Antibody (N-term) Blocking Peptide
BP7457b: EN2 Antibody (C-term) Blocking Peptide
BP7457d: EN2 Antibody (C-term-2) Blocking Peptide
BP7457e: EN2 Antibody (N-term) Blocking Peptide
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BACKGROUND
Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system.
REFERENCES
Intronic single nucleotide polymorphisms of engrailed homeobox 2 modulate the disease vulnerability of autism in a han chinese population. Yang P, et al. Neuropsychobiology, 2010. PMID 20523082. Family-based studies indicate association of Engrailed 2 gene with autism in an Indian population. Sen B, et al. Genes Brain Behav, 2010 Mar 1. PMID 20050924. Autism-associated haplotype affects the regulation of the homeobox gene, ENGRAILED 2. Benayed R, et al. Biol Psychiatry, 2009 Nov 15. PMID 19615670. Haplotype analysis of the engrailed-2 gene in young-onset Parkinson's disease. Rissling I, et al. Neurodegener Dis, 2009. PMID 19270442. Engrailed-2 regulates genes related to vesicle formation and transport in cerebellar Purkinje cells. Holst MI, et al. Mol Cell Neurosci, 2008 Aug. PMID 18562208.
