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EPHX1 predesign siRNASynthetic RNA

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United States
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Ordering Information
Catalog # Size Availability Price  
RI11808 5 OD 400 ul 13-15 days $ 110.00 Add to cart
  • Specification
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EPHX1 predesign siRNA - Additional info

Gene ID2052
Gene SymbolEPHX1
Other Names
MEH, EPHX, EPOX, EPHX1
Format
HPLC purified siRNA is supplied as a dried pellet in nmol quantities.
Storage
Maintain refrigerated at 2-8°C for up to one week. For long term storage store at -20°C.
Precautions
This product is for research use only. Not for use in diagnostic or therapeutic procedures.

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Provided below are standard protocols that you may find useful for product applications.

BACKGROUND

Epoxide hydrolase is a critical biotransformation enzyme that converts epoxides from the degradation of aromatic compounds to trans-dihydrodiols which can be conjugated and excreted from the body. Epoxide hydrolase functions in both the activation and detoxification of epoxides. Mutations in this gene cause preeclampsia, epoxide hydrolase deficiency or increased epoxide hydrolase activity. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

REFERENCES

Association of COPD candidate genes with CT emphysema and airway phenotypes in severe COPD. Kim WJ, et al. Eur Respir J, 2010 Jun 4. PMID 20525719. EPHX1 polymorphisms, COPD and asthma in 47,000 individuals and in meta-analysis. Lee J, et al. Eur Respir J, 2010 Jun 1. PMID 20516053. A case-control study of Parkinson's disease and tobacco use: gene-tobacco interactions. De Palma G, et al. Mov Disord, 2010 May 15. PMID 20461808. A Large-scale genetic association study of esophageal adenocarcinoma risk. Liu CY, et al. Carcinogenesis, 2010 Jul. PMID 20453000. Alcohol, tobacco and genetic susceptibility in relation to cancers of the upper aerodigestive tract in northern Italy. Canova C, et al. Tumori, 2010 Jan-Feb. PMID 20437850.