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FOS predesign siRNASynthetic RNA
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| RI12045 | 5 OD 400 ul | 13-15 days | $ 110.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
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- Backgrounds
FOS predesign siRNA - Additional info | |
| Gene ID | 2353 |
| Gene Symbol | FOS |
| Other Names AP-1, C-FOS, FOS | |
| Format HPLC purified siRNA is supplied as a dried pellet in nmol quantities. | |
| Storage Maintain refrigerated at 2-8°C for up to one week. For long term storage store at -20°C. | |
| Precautions This product is for research use only. Not for use in diagnostic or therapeutic procedures. | |
FOS predesign siRNA - Related products
AP3314a: Phospho-FOS-T232 Antibody
AP6585b: c-fos Antibody (C-term)
LY11468a: FOS Over-expression Lysate
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Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.
REFERENCES
Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls. Schuurhof A, et al. Pediatr Pulmonol, 2010 Jun. PMID 20503287. Ligand-specific c-Fos expression emerges from the spatiotemporal control of ErbB network dynamics. Nakakuki T, et al. Cell, 2010 May 28. PMID 20493519. Association study of 182 candidate genes in anorexia nervosa. Pinheiro AP, et al. Am J Med Genet B Neuropsychiatr Genet, 2010 Jul. PMID 20468064. Protein kinase C isoforms zeta and iota mediate collagenase expression and cartilage destruction via STAT3- and ERK-dependent c-fos induction. Litherland GJ, et al. J Biol Chem, 2010 Jul 16. PMID 20463008. cAMP-response element-binding protein (CREB) controls MSK1-mediated phosphorylation of histone H3 at the c-fos promoter in vitro. Shimada M, et al. J Biol Chem, 2010 Mar 26. PMID 20089855.
