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HEYL predesign siRNASynthetic RNA

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United States
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Ordering Information
Catalog # Size Availability Price  
RI12443 5 OD 400 ul 13-15 days $ 110.00 Add to cart
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HEYL predesign siRNA - Additional info

Gene ID26508
Gene SymbolHEYL
Other Names
HEY3, HRT3, bHLHb33, MGC12623, HEYL
Format
HPLC purified siRNA is supplied as a dried pellet in nmol quantities.
Storage
Maintain refrigerated at 2-8°C for up to one week. For long term storage store at -20°C.
Precautions
This product is for research use only. Not for use in diagnostic or therapeutic procedures.

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Provided below are standard protocols that you may find useful for product applications.

BACKGROUND

This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The sequence of the encoded protein contains a conserved bHLH and orange domain, but its YRPW motif has diverged from other HESR family members. It is thought to be an effector of Notch signaling and a regulator of cell fate decisions. Alternatively spliced transcript variants have been found, but their biological validity has not been determined.

REFERENCES

Towards a proteome-scale map of the human protein-protein interaction network. Rual JF, et al. Nature, 2005 Oct 20. PMID 16189514. Hesr, a mediator of the Notch signaling, functions in heart and vessel development. Kokubo H, et al. Trends Cardiovasc Med, 2005 Jul. PMID 16165016. Functional proteomics mapping of a human signaling pathway. Colland F, et al. Genome Res, 2004 Jul. PMID 15231748. HES and HERP families: multiple effectors of the Notch signaling pathway. Iso T, et al. J Cell Physiol, 2003 Mar. PMID 12548545. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.