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ITGA4 predesign siRNASynthetic RNA
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| RI12780 | 5 OD 400 ul | 13-15 days | $ 110.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
ITGA4 predesign siRNA - Additional info | |
| Gene ID | 3676 |
| Gene Symbol | ITGA4 |
| Other Names IA4, CD49D, MGC90518, ITGA4 | |
| Format HPLC purified siRNA is supplied as a dried pellet in nmol quantities. | |
| Storage Maintain refrigerated at 2-8°C for up to one week. For long term storage store at -20°C. | |
| Precautions This product is for research use only. Not for use in diagnostic or therapeutic procedures. | |
ITGA4 predesign siRNA - Related products
RI12780: ITGA4 predesign siRNA
DC08987: Human ITGA4 cDNA Clone
AT2564a: ITGA4 Antibody (monoclonal) (M01)
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Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
The product of this gene belongs to the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an alpha 4 chain. Unlike other integrin alpha chains, alpha 4 neither contains an I-domain, nor undergoes disulfide-linked cleavage. Alpha 4 chain associates with either beta 1 chain or beta 7 chain.
REFERENCES
Integrin alpha4beta1 signaling is required for lymphangiogenesis and tumor metastasis. Garmy-Susini B, et al. Cancer Res, 2010 Apr 15. PMID 20388801. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614. TAp63 regulates VLA-4 expression and chronic lymphocytic leukemia cell migration to the bone marrow in a CD74-dependent manner. Binsky I, et al. J Immunol, 2010 May 1. PMID 20357260. Multiple common variants for celiac disease influencing immune gene expression. Dubois PC, et al. Nat Genet, 2010 Apr. PMID 20190752. A small molecule that inhibits the interaction of paxillin and alpha 4 integrin inhibits accumulation of mononuclear leukocytes at a site of inflammation. Kummer C, et al. J Biol Chem, 2010 Mar 26. PMID 20097761.
