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LYVE1 predesign siRNASynthetic RNA

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United States
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Ordering Information
Catalog # Size Availability Price  
RI13109 5 OD 400 ul 13-15 days $ 110.00 Add to cart
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LYVE1 predesign siRNA - Additional info

Gene ID10894
Gene SymbolLYVE1
Other Names
HAR, XLKD1, LYVE-1, CRSBP-1, LYVE1
Format
HPLC purified siRNA is supplied as a dried pellet in nmol quantities.
Storage
Maintain refrigerated at 2-8°C for up to one week. For long term storage store at -20°C.
Precautions
This product is for research use only. Not for use in diagnostic or therapeutic procedures.

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Provided below are standard protocols that you may find useful for product applications.

BACKGROUND

This gene encodes a type I integral membrane glycoprotein. The encoded protein acts as a receptor and binds to both soluble and immobilized hyaluronan. This protein may function in lymphatic hyaluronan transport and have a role in tumor metastasis.

REFERENCES

Lymphatic vascularisation and involvement of Lyve-1+ macrophages in the human onchocerca nodule. Attout T, et al. PLoS One, 2009 Dec 9. PMID 20011036. Expression of LYVE-1 in sinusoidal endothelium is reduced in chronically inflamed human livers. Arimoto J, et al. J Gastroenterol, 2010 Mar. PMID 19908110. [Expression of lymphatic vessel endothelial hyaluronan receptor-1 in human colorectal cancer and its clinical significance] Li ZX, et al. Zhonghua Wei Chang Wai Ke Za Zhi, 2009 Sep. PMID 19742347. LYVE-1 immunocytochemical staining for gastrointestinal carcinoids. Tomita T. Pathology, 2009. PMID 19291537. A mechanism of sialylation functionally silences the hyaluronan receptor LYVE-1 in lymphatic endothelium. Nightingale TD, et al. J Biol Chem, 2009 Feb 6. PMID 19033446.