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NOS3 predesign siRNASynthetic RNA
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| RI13633 | 5 OD 400 ul | 13-15 days | $ 110.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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NOS3 predesign siRNA - Additional info | |
| Gene ID | 4846 |
| Gene Symbol | NOS3 |
| Other Names eNOS, ECNOS, NOS3 | |
| Format HPLC purified siRNA is supplied as a dried pellet in nmol quantities. | |
| Storage Maintain refrigerated at 2-8°C for up to one week. For long term storage store at -20°C. | |
| Precautions This product is for research use only. Not for use in diagnostic or therapeutic procedures. | |
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BACKGROUND
Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Multiple transcript variants encoding different isoforms have been found for this gene.
REFERENCES
Association between the Glu298Asp and T(-786)C polymorphisms of the endothelial nitric oxide synthase gene and respiratory distress in preterm neonates. Sivasli E, et al. Turk J Pediatr, 2010 Mar-Apr. PMID 20560249. Endothelial Nitric Oxide Synthase and Angiotensinogen Gene Polymorphism in Coronary Artery Diseases in Egypt. Motawi T, et al. Angiology, 2010 Jun 13. PMID 20547537. Association of the genetic polymorphisms of the ACE gene and the eNOS gene with lupus nephropathy in northern Chinese population. Li X, et al. BMC Med Genet, 2010 Jun 14. PMID 20540812. Impact of genomic polymorphism on arterial hypertension after aortic coarctation repair. Hager A, et al. Int J Cardiol, 2010 May 26. PMID 20537417. Endothelial nitric oxide synthase gene haplotypes affect nitrite levels in black subjects. Metzger IF, et al. Pharmacogenomics J, 2010 Jun 8. PMID 20531373.
