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PBK predesign siRNASynthetic RNA

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United States
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Ordering Information
Catalog # Size Availability Price  
RI13823 5 OD 400 ul 13-15 days $ 110.00 Add to cart
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Provided below are standard protocols that you may find useful for product applications.

BACKGROUND

This genes encodes a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. This mitotic kinase may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis.

REFERENCES

Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614. PBK/TOPK in the differential diagnosis of cholangiocarcinoma from hepatocellular carcinoma and its involvement in prognosis of human cholangiocarcinoma. He F, et al. Hum Pathol, 2010 Mar. PMID 19954816. Critical roles of T-LAK cell-originated protein kinase in cytokinesis. Park JH, et al. Cancer Sci, 2010 Feb. PMID 19900192. Molecular genetics of successful smoking cessation: convergent genome-wide association study results. Uhl GR, et al. Arch Gen Psychiatry, 2008 Jun. PMID 18519826. Bidirectional signals transduced by TOPK-ERK interaction increase tumorigenesis of HCT116 colorectal cancer cells. Zhu F, et al. Gastroenterology, 2007 Jul. PMID 17631144.