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PHLPP2 predesign siRNASynthetic RNA

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United States
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Ordering Information
Catalog # Size Availability Price  
RI13966 5 OD 400 ul 13-15 days $ 110.00 Add to cart
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PHLPP2 predesign siRNA - Additional info

Gene ID23035
Gene SymbolPHLPP2
Other Names
PHLPPL, KIAA0931, PHLPP2
Format
HPLC purified siRNA is supplied as a dried pellet in nmol quantities.
Storage
Maintain refrigerated at 2-8°C for up to one week. For long term storage store at -20°C.
Precautions
This product is for research use only. Not for use in diagnostic or therapeutic procedures.

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Provided below are standard protocols that you may find useful for product applications.

REFERENCES

Mst1 is an interacting protein that mediates PHLPPs' induced apoptosis. Qiao M, et al. Mol Cell, 2010 May 28. PMID 20513427. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614. Defining the human deubiquitinating enzyme interaction landscape. Sowa ME, et al. Cell, 2009 Jul 23. PMID 19615732. Common polymorphism in the phosphatase PHLPP2 results in reduced regulation of Akt and protein kinase C. Brognard J, et al. J Biol Chem, 2009 May 29. PMID 19324870. Depletion of Pleckstrin homology domain leucine-rich repeat protein phosphatases 1 and 2 by Bcr-Abl promotes chronic myelogenous leukemia cell proliferation through continuous phosphorylation of Akt isoforms. Hirano I, et al. J Biol Chem, 2009 Aug 14. PMID 19261608.