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PIAS2 predesign siRNASynthetic RNA
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| RI13978 | 5 OD 400 ul | 13-15 days | $ 110.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
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PIAS2 predesign siRNA - Additional info | |
| Gene ID | 9063 |
| Gene Symbol | PIAS2 |
| Other Names miz, MIZ1, SIZ2, PIASX, ZMIZ4, MGC102682, PIASX-BETA, PIASX-ALPHA, PIAS2 | |
| Format HPLC purified siRNA is supplied as a dried pellet in nmol quantities. | |
| Storage Maintain refrigerated at 2-8°C for up to one week. For long term storage store at -20°C. | |
| Precautions This product is for research use only. Not for use in diagnostic or therapeutic procedures. | |
PIAS2 predesign siRNA - Related products
AP1280b: PIAS2 (PIASny) Antibody (Center)
AP1246a: PIAS2 (PIASx1/2) Antibody (N-term)
AP1247a: PIAS2 (PIASx1/2) Antibody (C-term)
AP1248a: PIAS2 (PIASx1) Antibody (C-term)
RI13978: PIAS2 predesign siRNA
DC04039: Human PIAS2 cDNA Clone
LY11595a: PIAS2 Over-expression Lysate
BP1246a: PIASx1/2 Antibody (N-term) Blocking Peptide
BP1247a: PIASx1/2 Antibody (C-term) Blocking Peptide
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Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This gene encodes a protein involved in the regulation of transcription factors involved in MAP kinase signaling. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1. Two alternatively spliced transcripts encoding different isoforms have been described.
REFERENCES
Insights into strand exchange in BTB domain dimers from the crystal structures of FAZF and Miz1. Stogios PJ, et al. J Mol Biol, 2010 Jul 30. PMID 20493880. The Arf tumor suppressor protein inhibits Miz1 to suppress cell adhesion and induce apoptosis. Herkert B, et al. J Cell Biol, 2010 Mar 22. PMID 20308430. BCL6 suppression of BCL2 via Miz1 and its disruption in diffuse large B cell lymphoma. Saito M, et al. Proc Natl Acad Sci U S A, 2009 Jul 7. PMID 19549844. A ribosomal protein L23-nucleophosmin circuit coordinates Mizl function with cell growth. Wanzel M, et al. Nat Cell Biol, 2008 Sep. PMID 19160485. Miz1 and HectH9 regulate the stability of the checkpoint protein, TopBP1. Herold S, et al. EMBO J, 2008 Nov 5. PMID 18923429.
