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RANBP9 predesign siRNASynthetic RNA
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| RI14446 | 5 OD 400 ul | 13-15 days | $ 110.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
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- Backgrounds
RANBP9 predesign siRNA - Additional info | |
| Gene ID | 10048 |
| Gene Symbol | RANBP9 |
| Other Names BPM-L, BPM90, RANBPM, RanBP7, RANBP9 | |
| Format HPLC purified siRNA is supplied as a dried pellet in nmol quantities. | |
| Storage Maintain refrigerated at 2-8°C for up to one week. For long term storage store at -20°C. | |
| Precautions This product is for research use only. Not for use in diagnostic or therapeutic procedures. | |
RANBP9 predesign siRNA - Related products
AP8501c: RANBP9 Antibody (Center)
RI14446: RANBP9 predesign siRNA
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BACKGROUND
This gene encodes a protein that binds RAN, a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The protein encoded by this gene has also been shown to interact with several other proteins, including met proto-oncogene, homeodomain interacting protein kinase 2, androgen receptor, and cyclin-dependent kinase 11.
REFERENCES
RanBPM contributes to TrkB signaling and regulates brain-derived neurotrophic factor-induced neuronal morphogenesis and survival. Yin YX, et al. J Neurochem, 2010 Jul. PMID 20403074. Identification of RanBP 9/10 as interacting partners for protein kinase C (PKC) gamma/delta and the D1 dopamine receptor: regulation of PKC-mediated receptor phosphorylation. Rex EB, et al. Mol Pharmacol, 2010 Jul. PMID 20395553. Aire's partners in the molecular control of immunological tolerance. Abramson J, et al. Cell, 2010 Jan 8. PMID 20085707. RanBPM has proapoptotic activities that regulate cell death pathways in response to DNA damage. Atabakhsh E, et al. Mol Cancer Res, 2009 Dec. PMID 19996306. A fragment of the scaffolding protein RanBP9 is increased in Alzheimer's disease brains and strongly potentiates amyloid-beta peptide generation. Lakshmana MK, et al. FASEB J, 2010 Jan. PMID 19729516.
