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UBE4A predesign siRNASynthetic RNA
| Country | United States
Ordering Information
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|---|---|---|---|---|
| Catalog # | Size | Availability | Price | |
| RI15590 | 5 OD 400 ul | 13-15 days | $ 110.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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- Citiations : 0
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UBE4A predesign siRNA - Additional info | |
| Gene ID | 9354 |
| Gene Symbol | UBE4A |
| Other Names E4, UFD2, UBOX2, KIAA0126, MGC133315, UBE4A | |
| Format HPLC purified siRNA is supplied as a dried pellet in nmol quantities. | |
| Storage Maintain refrigerated at 2-8°C for up to one week. For long term storage store at -20°C. | |
| Precautions This product is for research use only. Not for use in diagnostic or therapeutic procedures. | |
UBE4A predesign siRNA - Related products
AP2110b: UBE4A Antibody (C-term)
RI15590: UBE4A predesign siRNA
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BACKGROUND
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly.
REFERENCES
CBP and p300 are cytoplasmic E4 polyubiquitin ligases for p53. Shi D, et al. Proc Natl Acad Sci U S A, 2009 Sep 22. PMID 19805293. Autoantibodies against ubiquitination factor E4A (UBE4A) are associated with severity of Crohn's disease. Sakiyama T, et al. Inflamm Bowel Dis, 2008 Mar. PMID 18069675. [Differential expression of USP2, USP14 and UBE4A between ovarian serous cystadenocarcinoma and adjacent normal tissues] Yang Y, et al. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi, 2007 Jun. PMID 17553343. Large-scale mapping of human protein-protein interactions by mass spectrometry. Ewing RM, et al. Mol Syst Biol, 2007. PMID 17353931. Ufd2, a novel autoantigen in scleroderma, regulates sister chromatid separation. Spinette S, et al. Cell Cycle, 2004 Dec. PMID 15611659.