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Rad51 (175 - 190) (CDB55)
Synthetic Peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P37383 |
|---|---|
| Other Accession | P70099, Q08297, Q8MKI8, O77507, Q2KJ94 |
| Sequence | NH2-AERYGLSGSDVLDNVA-COOH |
| Gene ID | 396086 |
|---|---|
| Other Names | DNA repair protein RAD51 homolog 1, RAD51A, RAD51 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | RAD51A |
|---|---|
| Synonyms | RAD51 |
| Function | Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination (HR). Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Recruited to resolve stalled replication forks during replication stress. Also involved in interstrand cross-link repair. |
| Cellular Location | Nucleus {ECO:0000250|UniProtKB:Q06609}. Cytoplasm {ECO:0000250|UniProtKB:Q06609}. Chromosome {ECO:0000250|UniProtKB:Q06609}. Note=Accumulated at sites of DNA damage. Recruited to stalled replication forks during replication stress. {ECO:0000250|UniProtKB:Q06609} |
| Tissue Location | Expressed at high levels in lymphoid and reproductive organs. |
Research Areas
Citations (0)
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Application Protocols
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$ 277.78
Cat# SP2142b
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