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Dermaseptin

Synthetic Peptide

     
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Product Information
Primary Accession P24302
Sequence NH2-ALWKTMLKKLGTMALHAGKAALGAAADTISQGTQ-COOH
Additional Information
Other Names Dermaseptin-1, DS I, Dermaseptin-S1, DS1, DMS1
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name DRS1
Function Antimicrobial activity with potent activity against Gram- positive and Gram-negative bacteria, fungi and protozoa (PubMed:1909573, PubMed:8306981, PubMed:8294443). Also stimulates the microbicidal activity of polymorphonuclear leukocytes (PubMed:9647785). Probably acts by disturbing membrane functions with its amphipathic structure (PubMed:8306981). Does not show cytotoxicity on lymphocytes or KB cells (PubMed:8294443). Does not show hemolytic activity (PubMed:1909573, PubMed:8294443, PubMed:21262294). In vitro, shows spermicidal, antiviral, and anti-leishmanial activities (PubMed:16307969, PubMed:16140737, PubMed:21262294).
Cellular Location Secreted
Tissue Location Expressed by the skin glands.
Research Areas
Citations (0)
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$ 277.78
Cat# SP2153b
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Availability: 2-3 weeks
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