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HIF - 1 {alpha} (556 - 574)
Synthetic Peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q98SW2 |
|---|---|
| Other Accession | Q9I8A9, Q9YIB9, Q309Z6, Q0PGG7, Q9XTA5 |
| Sequence | NH2-DLDLEMLAPYIPMDDDFQL-COOH |
| Gene ID | 100135944 |
|---|---|
| Other Names | Hypoxia-inducible factor 1-alpha, HIF-1-alpha, HIF1-alpha, hif1a |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | hif1a |
|---|---|
| Function | Functions as a master transcriptional regulator of the adaptive response to hypoxia. Under hypoxic conditions, activates the transcription of over 40 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, HILPDA, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. Plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. |
| Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q16665}. Nucleus {ECO:0000250|UniProtKB:Q16665}. Nucleus speckle {ECO:0000250|UniProtKB:Q61221}. Note=Cytoplasmic in normoxia, nuclear translocation in response to hypoxia. {ECO:0000250|UniProtKB:Q16665} |
Research Areas
Citations (0)
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Submit your citation using an Abcepta antibody to
info@abcepta.com, and receive a free "I Love Antibodies" mug.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
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$ 277.78
Cat# SP2191a
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