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>   home   >   Products   >   Peptides   >   Synthetic Peptides   >   Rad51 (179 - 190)   

Rad51 (179 - 190)

Synthetic Peptide

Product Information
Primary Accession O77507
Other Accession Q08297, Q06609, P70099, Q2KJ94, P37383
Calculated MW 1145.2 Da
Additional Information
Gene ID 100008661
Other Names DNA repair protein RAD51 homolog 1, RAD51
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RAD51
Function Participates in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Underwinds duplex DNA and forms helical nucleoprotein filaments. Part of a PALB2- scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3 (By similarity).
Cellular Location Nucleus. Cytoplasm. Cytoplasm, perinuclear region. Mitochondrion matrix. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Colocalizes with RAD51AP1 and RPA2 to multiple nuclear foci upon induction of DNA damage DNA damage induces an increase in nuclear levels. Together with FIGNL1, redistributed in discrete nuclear DNA damage-induced foci after ionizing radiation (IR) or camptothecin (CPT) treatment Accumulated at sites of DNA damage in a SPIDR-dependent manner (By similarity).
Research Areas
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Cat# SP2250a
(40 western blots)
Availability: Inquire
Bulk Size
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