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TRP - 2 (180 - 188)

Synthetic Peptide

     
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Product Information
Primary Accession P29812
Other Accession P40126
Peptide ID 8042934
Calculated MW 1175.4 Da
Sequence NH2-SVYDFFVWL-COOH
Additional Information
Gene ID 13190
Other Names L-dopachrome tautomerase, DCT, DT, L-dopachrome Delta-isomerase, SLATY locus protein, Tyrosinase-related protein 2, TRP-2, TRP2, Dct, Tyrp-2, Tyrp2
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Dct
Synonyms Tyrp-2, Tyrp2
Function Catalyzes the conversion of L-dopachrome into 5,6- dihydroxyindole-2-carboxylic acid (DHICA) (PubMed:1537333). Involved in regulating eumelanin and phaeomelanin levels.
Cellular Location Melanosome membrane {ECO:0000250|UniProtKB:P40126}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:P40126}. Melanosome. Note=Proper trafficking to melanosome is regulated by SGSM2, ANKRD27, RAB9A, RAB32 and RAB38
Tissue Location Melanocytes and retinal pigmented epithelium.
Research Areas
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Cat# SP2432b
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