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Presenilin-2 N-Terminal Peptide

Synthetic Peptide

Product Information
Primary Accession P49810
Other Accession Q5RCN9
Calculated MW 1718.73 Da
Additional Information
Gene ID 5664
Other Names Presenilin-2, PS-2, 3423-, AD3LP, AD5, E5-1, STM-2, Presenilin-2 NTF subunit, Presenilin-2 CTF subunit, PSEN2, AD4, PS2, PSNL2, STM2
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PSEN2
Synonyms AD4, PS2, PSNL2, STM2
Function Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. May function in the cytoplasmic partitioning of proteins.
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein
Tissue Location Isoform 1 is seen in the placenta, skeletal muscle and heart while isoform 2 is seen in the heart, brain, placenta, liver, skeletal muscle and kidney
Research Areas
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Cat# SP2553a
(40 western blots)
Availability: Inquire
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