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Synthetic Peptide

Product Information
Primary Accession P68409
Other Accession P68408, P59262, P01501, Q8LW54
Peptide ID 10030332
Calculated MW 2846.46 Da
Additional Information
Other Names Melittin, MELT
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function Main toxin of bee venom with strong hemolytic activity. Integrates into cell membranes and has multiple effects, probably, as a result of its interaction with negatively charged phospholipids. It inhibits well known transport pumps such as the Na(+)-K(+)-ATPase and the H(+)-K(+)-ATPase. Increases the permeability of cell membranes to ions, particularly Na(+) and indirectly Ca(2+), because of the Na(+)-Ca(2+)-exchange (By similarity).
Cellular Location Secreted. Target cell membrane. Note=Forms a transmembrane alpha-helix in the target cell membrane. Forms a membrane channel in the prey (By similarity).
Tissue Location Expressed by the venom gland.
Research Areas
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Cat# SP2730b
(40 western blots)
Availability: Inquire
Bulk Size
Seasonal Special on Bulk Order
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Ordering Information

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