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CREBtide

Synthetic Peptide

     
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Product Information
Primary Accession P27925
Sequence NH2-KRREILSRRPSYR-COOH
Additional Information
Gene ID 281713
Other Names Cyclic AMP-responsive element-binding protein 1, CREB-1, cAMP-responsive element-binding protein 1, Cyclic AMP-responsive DNA-binding protein, CREB1, CREB, CREB2
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CREB1
Synonyms CREB, CREB2
Function Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters (PubMed:1309910, PubMed:8057465, PubMed:8627725). Transcription activation is enhanced by the TORC coactivators which act independently of Ser-117 phosphorylation (By similarity). Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells (By similarity). Regulates the expression of apoptotic and inflammatory response factors in cardiomyocytes in response to ERFE-mediated activation of AKT signaling (By similarity).
Cellular Location Nucleus.
Research Areas
Citations (0)
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$ 277.78
Cat# SP2911b
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Availability: 2-3 weeks
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