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> home > Products > Peptides > Synthetic Peptides > Platelet Membrane Glycoprotein IIB Peptide (296-306)
Platelet Membrane Glycoprotein IIB Peptide (296-306)
Synthetic Peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9QUM0 |
|---|---|
| Other Accession | P08514 |
| Sequence | NH2-TDVNGDGRHDL-COOH |
| Gene ID | 16399 |
|---|---|
| Other Names | Integrin alpha-IIb, GPalpha IIb, GPIIb, Platelet membrane glycoprotein IIb, CD41, Integrin alpha-IIb heavy chain, Integrin alpha-IIb light chain, Itga2b |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | Itga2b |
|---|---|
| Function | Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface. |
| Cellular Location | Membrane; Single-pass type I membrane protein. |
Research Areas
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$ 277.78
Cat# SP3176a
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