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>   home   >   Products   >   Peptides   >   Synthetic Peptides   >   Platelet Membrane Glycoprotein IIB Peptide (296-306)   

Platelet Membrane Glycoprotein IIB Peptide (296-306)

Synthetic Peptide

     
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Product Information
Primary Accession Q9QUM0
Other Accession P08514
Calculated MW 1198.21 Da
Sequence NH2-TDVNGDGRHDL-COOH
Additional Information
Gene ID 16399
Other Names Integrin alpha-IIb, GPalpha IIb, GPIIb, Platelet membrane glycoprotein IIb, CD41, Integrin alpha-IIb heavy chain, Integrin alpha-IIb light chain, Itga2b
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Itga2b
Function Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha- IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.
Cellular Location Membrane; Single-pass type I membrane protein
Research Areas
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Cat# SP3176a
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