|Calculated MW||2272.56 Da|
|Other Names||Prolactin-releasing peptide, PrRP, Prolactin-releasing hormone, Prolactin-releasing peptide PrRP31, Prolactin-releasing peptide PrRP20, PRLH, PRH|
|Format||Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Stimulates prolactin (PRL) release and regulates the expression of prolactin through its receptor GPR10. May stimulate lactotrophs directly to secrete PRL.|
|Tissue Location||Medulla oblongata and hypothalamus. EMBL; AB015419; BAA29027.1; -; mRNA EMBL; BC069081; AAH69081.1; -; mRNA EMBL; BC069284; AAH69284.1; -; mRNA CCDS; CCDS2519.1; - RefSeq; NP_056977.1; NM_015893.1 UniGene; Hs.247710; - ProteinModelPortal; P81277; - STRING; 9606.ENSP00000165524; - iPTMnet; P81277; - PhosphoSitePlus; P81277; - BioMuta; PRLH; - DMDM; 8134649; - PaxDb; P81277; - PRIDE; P81277; - Ensembl; ENST00000165524; ENSP00000165524; ENSG00000071677 GeneID; 51052; - KEGG; hsa:51052; - CTD; 51052; - DisGeNET; 51052; - GeneCards; PRLH; - HGNC; HGNC:17945; PRLH HPA; HPA014768; - MIM; 602663; gene neXtProt; NX_P81277; - OpenTargets; ENSG00000071677; - PharmGKB; PA134927756; - eggNOG; ENOG410J49T; Eukaryota eggNOG; ENOG4111800; LUCA GeneTree; ENSGT00390000005489; - HOGENOM; HOG000115720; - HOVERGEN; HBG004601; - InParanoid; P81277; - KO; K05269; - OMA; INPAWYA; - OrthoDB; EOG091G191K; - PhylomeDB; P81277; - TreeFam; TF330717; - BioCyc; ZFISH:ENSG00000071677-MONOMER; - Reactome; R-HSA-375276; Peptide ligand-binding receptors GeneWiki; PRLH; - GeneWiki; Prolactin-releasing_peptide; - GenomeRNAi; 51052; - PRO; PR:P81277; - Proteomes; UP000005640; Chromosome 2 Bgee; ENSG00000071677; - CleanEx; HS_PRLH; - ExpressionAtlas; P81277; baseline and differential Genevisible; P81277; HS GO; GO:0005737; C:cytoplasm; IEA:Ensembl GO; GO:0005576; C:extracellular region; TAS:Reactome GO; GO:0005179; F:hormone activity; TAS:ProtInc GO; GO:0048483; P:autonomic nervous system development; IEA:Ensembl GO; GO:0006112; P:energy reserve metabolic process; IEA:Ensembl GO; GO:0045444; P:fat cell differentiation; IEA:Ensembl GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IEA:Ensembl GO; GO:0006629; P:lipid metabolic process; IEA:Ensembl GO; GO:0002023; P:reduction of food intake in response to dietary excess; IEA:Ensembl GO; GO:0040014; P:regulation of multicellular organism growth; IEA:Ensembl GO; GO:0009749; P:response to glucose; IEA:Ensembl GO; GO:0032868; P:response to insulin; IEA:Ensembl GO; GO:0001894; P:tissue homeostasis; IEA:Ensembl InterPro; IPR026194; PrRP PANTHER; PTHR17206; PTHR17206; 1 Pfam; PF15172; Prolactin_RP; 1 2: Evidence at transcript level; Amidation; Cleavage on pair of basic residues; Complete proteome; Hormone; Reference proteome; Secreted; Signal SIGNAL 1 22 PEPTIDE 23 53 Prolactin-releasing peptide PrRP31 /FTId=PRO_0000022144 PEPTIDE 34 53 Prolactin-releasing peptide PrRP20 /FTId=PRO_0000022145 PROPEP 58 87 /FTId=PRO_0000022146 MOD_RES 53 53 Phenylalanine amide. SEQUENCE 87 AA; 9639 MW; 229A2F3F50CF981B CRC64; MKVLRAWLLC LLMLGLALRG AASRTHRHSM EIRTPDINPA WYASRGIRPV GRFGRRRATL GDVPKPGLRP RLTCFPLEGG AMSSQDG|
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