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Neuromedin U, rat

Synthetic Peptide

     
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Product Information
Primary Accession P12760
Sequence NH2-YKVNEYQGPVAPSGGFFLFRPRN-CONH2
Additional Information
Gene ID 63887
Other Names Neuromedin-U, Neuromedin-U-23, NmU-23, Nmu
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Nmu
Function [Neuromedin-U-23]: Ligand for receptors NMUR1 and NMUR2 (PubMed:28874765). Receptor-binding is very tight if not irreversible and triggers an increase in the cytosolic Ca(2+) concentration (PubMed:28874765). Stimulates muscle contractions of specific regions of the gastrointestinal tract. In rat, NMU stimulates contractions of stomach circular muscle.
Cellular Location [Neuromedin-U-23]: Secreted
Tissue Location Expressed throughout the gastrointestinal tract with highest levels in the duodenum and jejunum (PubMed:7916966). Low levels in spinal cord, hypothalamus, and stomach (PubMed:7916966) Neuromedin-U-23: Expressed in the small intestine and the pituitary gland (at protein level) (PubMed:28874765). Neuromedin precursor- related peptides: Expressed in pituitary gland and small intestine (at protein level) (PubMed:28874765).
Research Areas
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$ 277.78
Cat# SP3367b
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