|Calculated MW||1154.33 Da|
|Other Names||Bradykinin-potentiating and C-type natriuretic peptides, Angiotensin-converting enzyme inhibitor, BPP-CNP homolog, Blomhotin, Bradykinin-potentiating peptide A, BPP-a, Potentiator A, Leu3-blomhotin, Potentiator D, Bradykinin-potentiating peptide B, BPP-b, Potentiator B, Bradykinin-potentiating peptide C, BPP-c, Potentiator C, Bradykinin-potentiating peptide E, BPP-e, Potentiator E, Bradykinin-potentiating peptide Ahb1, BPP-Ahb1, Bradykinin-potentiating peptide Ahb2, BPP-Ahb2, C-type natriuretic peptide, BNP|
|Format||Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Blomhotin: inhibits the rabbit lung angiotensin- converting enzyme (ACE) with an IC(50) of 15 uM. Bradykinin-potentiating peptide B: inhibits the activity of the angiotensin-converting enzyme (ACE) by a preferential interaction with its C-domain. Also potentiates the hypotensive effects of bradykinin. Inhibits the rabbit lung ACE with an IC(50) of 1.1 uM. Leu3-blomhotin: inhibits the rabbit lung angiotensin- converting enzyme (ACE) with an IC(50) of 46 uM. Synthetic Leu3- blomhotin contracts the rat gastric fundus smooth muscle in a rapid and transient manner. Bradykinin-potentiating peptide Ahb2: does not show any bradykinin-potentiating effects.|
|Tissue Location||Expressed by the venom gland.|
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