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Background
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VEGF3 is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D.
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Background
References
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- Byeon, J.S., et al., J. Gastroenterol. Hepatol. 19(6):648-654 (2004).
- Su, J.L., et al., Cancer Res. 64(2):554-564 (2004).
- Yan, C., et al., World J. Gastroenterol. 10(6):783-790 (2004).
- Hsieh, C.Y., et al., J. Biomed. Sci. 11(2):249-259 (2004).
- Liu, X.E., et al., World J. Gastroenterol. 10(3):352-355 (2004).
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List Price (USA): $235.00/0.1mg
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