|
Background
|
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.
|
Background
References
|
- Marzluff, W.F., et al., Genomics 80(5):487-498 (2002).
- Albig, W., et al., Hum. Genet. 101(3):284-294 (1997).
- Albig, W., et al., Hum. Genet. 97(4):486-491 (1996).
|
Order Information
List Price (USA): $235.00/0.1mg
Related Products
Data Rewards Program
