|
Background
|
JHDM1a/FBXL11 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box),which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. JHDM1a/FBXL11 belongs to the Fbls class and, in addition to an F-box, contains at least 6 highly degenerated leucine-rich repeats.
|
Background
References
|
- Tsukada,Y.,Nature 439 (7078), 811-816 (2006)
- Andersen,J.S.,Nature 433 (7021), 77-83 (2005)
|
Order Information
List Price (USA): $235.00/0.1mg
Related Products
Data Rewards Program
