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Background
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JMJD2A is a member of the Jumonji domain 2 (JMJD2) family and a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor.
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Background
References
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- Gray S.G., Iglesias A.H.J. Biol. Chem. 280:28507-28518(2005)
- Zhang D., Yoon H.-G.Mol. Cell. Biol. 25:6404-6414(2005)
- Whetstine J.R., Nottke A.Cell 125:467-481(2006)
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List Price (USA): $235.00/0.1mg
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