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Background
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Glycine N-methyltransferase (GNMT) catalyzes the synthesis of N-methylglycine (sarcosine) from glycine using S-adenosylmethionine (AdoMet) as the methyl donor. GNMT acts as an enzyme to regulate the ratio of S-adenosylmethionine to S-adenosylhomocysteine (AdoHcy) and participates in the detoxification pathway in liver cells.
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Background
References
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- Augoustides-Savvopoulou, P., et al., J. Inherit. Metab. Dis. 26(8):745-759 (2003).
- Tseng, T.L., et al., Cancer Res. 63(3):647-654 (2003).
- Luka, Z., et al., Hum. Genet. 110(1):68-74 (2002).
- Strausberg RL, et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002).
- Mudd, S.H., et al., J. Inherit. Metab. Dis. 24(4):448-464 (2001).
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List Price (USA): $99.00/0.1mg
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