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Background
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HTATIP belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction.
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Background
References
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- Cai, Y., et al., J. Biol. Chem. 280(14):13665-13670 (2005).
- Patel, J.H., et al., Mol. Cell. Biol. 24(24):10826-10834 (2004).
- Legube, G., et al., J. Biol. Chem. 279(43):44825-44833 (2004).
- Franzese, O., et al., Cell Death Differ. 11(7):782-784 (2004).
- Taubert, S., et al., Mol. Cell. Biol. 24(10):4546-4556 (2004).
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List Price (USA): $235.00/0.1mg
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